25 Years of Algipore®

Natural bone repair from the sea

Innovation from Nature: bone regeneration with Algipore® for the past 25 years

For implant treatment, augmentation is often necessary to create an adequate bone supply. It is not always possible to use autogenous bone because  dental practitioners are often faced with situations in which the patient’s own bone supply is inadequate. There’s Algipore® for these cases – and it’s been around for 25 years!

In the early 1980s Algipore® inventor Professor Rolf Ewers with his Kiel team embarked on the search for an alternative bone augmentation material to the synthetically produced calcium phosphate ceramics or hydroxyapatites of animal origin commonly used at the time. His goal: to find a natural substance for producing the replacement material, which would prove extremely similar to human bone and would be naturally porous, biological and of non-animal origin. In this search, Professor Ewers came across red algae, which deposit calcium carbonate in the cell walls for stabilization. Calcium is deposited in such a way that all the algal cells are in contact with each other via micropores. The Algipore® manufacturing process maintains this form of contact and allows communication between the bone-forming cells, e.g. through the exchange of signal molecules and growth factors. This communication provides the basis for the morphogenesis of new bone in the patient.

Another special feature: The mineral is largely absorbed in the body, thereby enabling new bone to form at the same time. As a result, reliable volume stability is guaranteed at all times. When the augmentation material is used, meshed newly formed bone structures like trabeculae are built up during the early healing phase, which allows for excellent remodeling. For Professor Ewers these were crucial reasons to use the material in clinical practice after the extremely promising, early results in animal studies. Algipore® now celebrates more than 25 years as a proven, excellent bone augmentation material.